App-safe HK / Shenzhen ops
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Must contactBiomanufacturing85

SiyoBio (Zhongke Xinyang)

深圳中科欣扬生物科技有限公司

A Shenzhen synthetic-biology company that runs microbial cell factories at industrial fermentation scale and sells COSMOS-certified skin actives (ectoin, ergothioneine) — a credible local fermentation + ingredient partner.

Location
Longgang District · Shenzhen
Visit window
From the Nanshan base · Jul 13–31
Source status
high confidenceprofiled

Next action

Prepare the private outreach route and meeting ask; keep contact details out of the app.

Why now: Visit window · From the Nanshan base · Jul 13–31

What they do

SiyoBio (Zhongke Xinyang, from a CAS lineage) designs engineered microbial strains and ferments them to produce skincare and anti-ageing actives, including ectoin and SYOMICRO-ERGO (ergothioneine). It operates a dedicated Industrialization Center for process scale-up and mass production (reportedly up to ~100 tonnes per tank, >99% purity) plus an Applied Research Center.

It holds FSSC22000, BRC, HACCP and HALAL food-safety certifications and EU COSMOS (ECOCERT) on several products.

Why it matters

High — lead fit is the biomanufacturing priority: pilot-to-industrial microbial fermentation with a real industrialization center and standardized process development, exactly the fermentation / scale-up capability Pure Advance needs for engineered microbial candidates. Its engineered-strain cell-factory model is on-theme for the discovery-plus-biomanufacturing platform.

Secondary: its actives (ectoin, ergothioneine) are soothing, barrier-protective antioxidants suited to the Coolvex topical line. The HALAL certification is a standout fit for a Saudi-based partner.

Visit objective & route

Meet on both fronts: CDMO / co-development for the engineered-microbial biocontrol platform (pilot→industrial fermentation), and buying validated actives (ectoin, ergothioneine) for the secondary Coolvex line; confirm whether they can show the Industrialization Center.

Approach route

Direct outreach for an appointment (they publish a direct channel); InnoX routing optional. Request a meeting at the Industrialization Center.

Talking points

  • Lead with the HALAL certification + Saudi-base hook (strongest single opener).
  • Do you take external CDMO / contract-manufacturing projects, or only run your own product lines?
  • What pilot-scale bioreactor sizes are available for a partner's process (the 100 t figure is your max, not necessarily pilot)?
  • Can you supply cosmetic-grade ectoin and SYOMICRO-ERGO ergothioneine with COSMOS / HALAL documentation for the topical (Coolvex) line?
  • Bring: Pure Advance one-pager; NDA template.

Open questions

  • Whether they take external CDMO / contract-manufacturing projects vs. only their own product lines.
  • Exact pilot-scale bioreactor sizes available for a partner's process (the 100 t figure is their max, not pilot).
  • GMP (pharma) vs. food/cosmetic-grade manufacturing status.
  • Whether the Longgang address is HQ/office only and where the fermentation plant physically sits.
  • KSA/GCC export capability, MOQ and sample availability; any post-2022 funding.

Risks & unknowns

  • Open third-party CDMO/tolling terms are not advertised; public model is own-products + co-development, not fee-for-service — confirm openness.
  • Pilot-scale reactor sizes for a partner's own process unconfirmed (100 t is max, not pilot).
  • GMP vs. food/cosmetic-grade status unverified; COA/INCI/CAS export docs presumed but unconfirmed.
  • Appointment-only; Longgang is across the city from Nanshan (~45–70 min); confirm plant location vs. office.

Private-pack boundary

Contact details, exact address, and appointment logistics are kept in your private pack — verify privately before outreach. This dossier holds public, app-safe intelligence only.